Patents
Glossary
| Agrobacterium | a naturally occurring soil bacterium that can be used to transfer genes into a plant cell and thus create a transgenic plant |
| Anti-fungal Protein | a protein that limits the growth of or kills a fungal pathogen |
| Bioassay | a biological test to assess whether a molecule limits the growth or kills a biological organism such as a fungus or an insect |
| Bt | Bacillus thuringiensis, a naturally occurring soil bacterium that produces insecticidal toxins |
| Bt Technology | an existing insect resistance technology which involves production of the Bt-insecticidal toxins in transgenic plants |
| Construct | a synthetic gene or series of genes that have been created in the laboratory. Constructs carry the genetic code for production of proteins of interest or a desired trait in a transgenic organism (eg a plant) |
| Defensin | an antifungal protein |
| Event | an event occurs when a transgene is inserted into the host DNA (eg the plant DNA). Different insertions are classified as separate events |
| Expression | when a gene is turned on to produce a protein |
| Freedom to Operate | rights to all the intellectual property needed to commercialise a transgenic plant |
| Fungal Pathogens | any fungus causing disease |
| Fusarium Wilt | a disease caused by Fusarium species which causes wilt in affected plants |
| Germplasm | the heredity material from an organism such as an elite plant cultivar (seed) |
| Heterozygous | any cell or organism having different genes at the same position in a pair of chromosomes. A hemizygous transgenic plant has only one copy of the transgene |
| Homozygous | any cell or organism having identical genes at the same position in a pair of chromosomes |
| Hybrid | the offspring of plants of different species or different varieties of the same species |
| MGEV | Hexima’s Multi-Gene Expression Vehicle, a technology which facilitates the production of multiple proteins in a plant from a single transgene |
| Peptide | a small chain of amino acids |
| Promoters | a piece of DNA that functions as a switch to turn genes on and off |
| Protein | a linear polymer of amino acids linked in a specific sequence determined by a gene |
| Proteinase | an enzyme that catalyses the splitting of proteins into smaller peptides and amino acids |
| Proteinase Inhibitors (PI’s) | proteins that inhibit the catalytic activity of proteinases |
| Stacking | the combination of several Traits in a crop seed |
| Selectable Marker | a gene and it’s product that can be used to select transgenic cells. For example, a gene that confers resistance to an antibiotic or a herbicide |
| Trait | a character conferred either by conventional breeding or by gene technology to a plant, such as insect resistance or fungal resistance |
| Transient Expression | temporary or short lived production of a protein from a transgene |
| Verticillium Wilt | a disease caused by Verticillium dahliae which causes wilt in affected plants |
Hexima’s granted patents are listed below. More information regarding our patents may be found by searching the WIPO PATENTSCOPE database.
Insecticidal proteins from plants and methods for their use WO/2019/178042
A Method of in vivo Treatment WO/2016/191790
A Method of Treatment WO/2016/061619
Agents and Methods of Treatment WO/2015/161348
Agents and Methods for Treatment of Pathogens WO/2015/161346
Anti Pathogenic Methods WO/2014/078900
Modified Plant Defensin Useful as Anti-Pathogenic Agents WO/2012/106759
Defensin variants and methods of use US2012/0054911
Plant Anti-Pathogen Systems WO/2010/015024
Antifungal Methods WO/2009/094719
Multi Gene Expression Vehicle WO/2007/137329
Nucleic acids encoding plant defensins and methods of use thereof WO/2004/001012
Plant-derived molecules and genetic sequences encoding same and uses thereof WO/2002/063011
Defensin polynucleotides and methods of use US2003/0041438